Vitamin D and effects on fertility


Vitamin D is mainly known for the role it plays in calcium absorption to ensure optimal well-being of bones and teeth. In reality, its function is much broader and relates to cardiovascular health, the immune response, diabetes. Furthermore, along with sex hormones, vitamin D modulates reproductive processes in both women and men.


L’ 80-90% of vitamin D is produced by the skin due to UVB rays, while a smaller quantity derives from diet and / or supplementation. Vitamin D from the skin and diet is metabolised in the liver to 25-hydroxyvitamin D, a form used to evaluate the state of vitamin D and classify it in a sufficient value if it is higher than 30 ng / ml, an insufficient value if it is between 20 and 29 ng / ml, deficiency if less than 20 ng / ml. The 25-hydroxyvitamin D form is converted at the renal level, but also at the level of many other tissues, into 1,25-dihydroxyvitamin D, which is the active form that acts through specific receptors for vitamin D distributed in various tissues such as the skeleton, parathyroid glands and reproductive tissues.


The correlation between seasons and exposure to sunlight with reproduction has been extensively studied: the circulating levels of 25-hydroxyvitamin D show seasonal variability with high levels in summer and autumn and low levels in winter and spring. In northern countries, where there is a strong contrast of brightness depending on the season, conception rates decrease during the dark winter months, while there is a peak of conception during the summer and consequently a peak of births during the spring.Many studies have shown effects of vitamin D on the results of in vitro fertilization pathways, on pathological conditions such as polycystic ovary syndrome (PCOS), endometriosis and on the quality of seminal fluid (sperm count, motility and morphology ). Vitamin D stimulates the production of steroid hormones: it is essential for the synthesis of estrogens in both sexes. Men with low levels of vitamin D show low testosterone levels and low percentage of motile and morphologically normal spermatozoa. Endometriosis has a pathogenesis related to inflammatory and immune-mediated processes: vitamin D is involved in the regulation of the immune system. A vitamin D deficiency is frequently present in women with polycystic ovary syndrome, the most common female endocrine disorder with a prevalence 5-10% in women of reproductive age. Many authors have highlighted a correlation between obesity and vitamin D deficiency, but it is unclear whether vitamin D insufficiency derives from obesity or vice versa. In these patients, increases in circulating vitamin D levels after careful therapy were related to normalization or improvement of menstrual cyclicity, acne and insulin resistance. A particularly interesting finding emerges from a study conducted among 101 young women in which it was highlighted an inverse correlation between vitamin D levels and progesterone and estradiol levels: high levels of vitamin D are associated with low risk of breast cancer due to the potential effect of reducing levels of estradiol and progesterone. Vitamin D deficiency is common in women during pregnancy due to an increased maternal and fetal consumption: this deficit is associated with an increased risk of gestational diabetes and other pregnancy complications such as gestational hypertension and preeclampsia, bacterial vaginosis, intrauterine growth retardation, preterm delivery. For these reasons, vitamin D supplementation is safe and effective from pregnancy to delivery.

Vegan Food Supplements


Vegan food supplements differ from common food supplements on the market, due to their intrinsic characteristic of having tested and certified ingredients, not deriving from animal sources and / or derived from them.

Supply chain control in production also certifies that there are no cross-contamination with other productions of food of animal origin or derivation.

NUTRA-BE, a young Italian company, through expertise and passion, studies its own formulations and develops specific vegan food supplements, designed to adapt to the needs of the customer who is most attentive to certain ethical issues, respecting the balance of nature and promoting mental health that physical.

The company NUTRA-BE certifies that all its vegan food supplements do not contain ingredients of animal origin and / or derived from them, not only in the active ingredient but also in the use of any sweeteners and adjuvants useful for the stability of the product.

All the raw materials that make up our formulations are certified by our suppliers as Vegan Friendly, OGM free, Gluten Free and, for almost all of our vegan food supplements, also Diabetic Friendly, as we use, where possible, a sweetener of origin natural that has a Glycemic Index almost equal to zero.

Folic Acid Vitamin B9


Folic acid or Vitamin B9 (Folate in the natural form), is a water-soluble vitamin belonging to the B vitamins that is taken exclusively through diet and is essential for pregnant women as it tends to protect and promote the development of the embryo.

Vitamin B9 is also essential for the synthesis of proteins and DNA as well as for the formation of hemoglobin. Works in synergy with vitamin B12 and B6 where it plays a role in the metabolism and in the control of the values ​​of homocysteine ​​(sulphured amino acid, of which a high concentration in the blood is considered a cardiovascular risk factor).

Its correct presence in the body therefore helps to protect against the risk of developing heart disease.

In which foods is vitamin B9 present

Vitamin B9, or folic acid, is mainly found in some foods such as green leafy vegetables (lettuce, broccoli, spinach, asparagus, Brussels sprouts), dried fruit (almonds, hazelnuts, walnuts), especially whole grain and legumes. in some fruits like oranges, kiwis, lemons, strawberries, avocados. Among the foods of animal origin there are eggs, liver, salmon, milk and derivatives.

Remember that fruits and vegetables should be eaten preferably raw because cooking degrades most of the folate present in foods.

What is the daily requirement of vitamin B9

The daily requirement of Ac.Folico is about 200 mcg. The amount is doubled (400mcg) during pregnancy, since the fetus uses the maternal reserves, and during breastfeeding.

Vitamin B9 deficiency

Vitamin B9 deficiency, or folic acid, can derive from incorrect lifestyles such as alcohol abuse, smoking, as well as the onset of certain diseases such as insulin-dependent diabetes mellitus and celiac disease that causes a reduced production of red blood cells in the blood, with consequent onset of megaloblastic anemia.

Vitamin B9 deficiency or folic acid in pregnant women can have negative effects on the proper development of the fetal nervous system. In some cases a high folic acid deficiency can cause the birth of premature babies and with spina bifida, which is a condition for which fetal development does not occur, the correct closure of the neural tube.

There are also drugs (antacids, some drugs used to lower blood cholesterol levels, non-steroidal anti-inflammatories and some diuretics) that lower the levels of folic acid in the body, so supplementation may be necessary.
Folic acid can also interact with other drugs (antiepileptic, chemotherapeutic) modifying its absorption and therefore its effects.

Islandic Cetraria source of Vitamin D3


The lichen of the species Cetraria Islandica, is a characteristic species of the lava expanses in Iceland, is a very rich source of vitamin D3.

Lichens are very particular vegetables in which the thallus consists of the association of a fungus (micobionte) and of an alga (fotobionte), between which a collaboration relationship called symbiosis is established.

This means that the two organisms live and grow together and that the life of one is closely linked and connected to that of the other, with a mutual advantage.

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Cladonia Rangiferina source of Vitamin D3


Plant information

Cladonia Rangiferina is also known as reindeer moss, reindeer lichen, because it is a vital source of food eaten by reindeer. It is a slightly colored plant that has a three-dimensional branching with a bushy appearance, belonging to the Cladoniaceae family.
The generic name of Cladonia Rangiferina derives from the Greek word “Kladon” which means sprout, due to its appearance similar to a shrub with its branched segments of lichen.

Source and description

Reindeer lichen is a slow-growing plant (3-5 mm per year), is extremely branched, each divided between three and four thicker branches. Colors range from whitish, gray or brownish gray. Form large mats up to 10 cm high, with branching to a smaller angle.
Lichens have two separate fungus and algae organisms, because of this successful combination the fungus provides moisture and minerals, in which photogenic algae provide photosynthetic nutrition. Lichen can survive for long periods of time without water. They dry and become dormant when there is little water or light. They can start to grow again even after long periods of dormancy.


Being a hard plant can grow in a variety of habitats from hot and cold climates that are well drained, open environments. Lichen is present in many pine forests and low alpine sites, in addition to rocky terrain and wetlands.

Medical uses in history

During the Middle Ages lichens were considered therapeutic. The natives of the North used it to treat colds, arthritis, fevers and other problems. It has also been used as a poultice to alleviate the pains of arthritic joints.

DHA docosahexaenoic acid


L’olio di alghe si ricava, direttamente dalle micro alghe del genere Schizochytrium sp. Quest’olio contiene DHA, che rappresenta il 97% dei grassi omega-3 nel cervello.

Algae oil is a plant source of DHA, a type of fat also known as docosahexaenoic acid: it is an essential supplement for those who do not take fish or derivatives such as fish oil with the diet.

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Vitamin B12


Vitamin B12 is part of the water-soluble B-group vitamins.

Our body is not able to synthesize this substance alone but must necessarily take it with food

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Liposomes and Liposomial Iron


The Liposomal Iron, is a preparation based on ferric pyrophosphate carried within a phospholipid membrane of vegetable origin (soya), which has compared to other formulations based on iron

  • high gastrointestinal absorption
  • high bioavailability
  • lower incidence of side effects


Absorption of ionic iron occurs mainly at the duodenal level and is mediated by specific carriers. Under normal conditions only 15-20% of the administered iron is absorbed, so it does not make sense to force the transport capacity of the carriers with high doses. The sophisticated incorporation technology in natural phospholipids makes the iron highly bioavailable, well tolerated and rapidly absorbed. The presence of the liposomal envelope, in fact, protecting the iron from contact with the gastric mucosa avoids the pro-oxidant effect of free iron. The liposomal protection allows the microelement to pass unimpaired the gastric environment to be absorbed directly at the level of the whole small intestine and not only duodenal. The transmission through liposomal technology corresponds, in our organism, to the transport of various substances by chylomicrons. These natural vehicles, in fact, are the dense and voluminous lipoproteins that represent the form of transport of food fats from the intestine to the various tissues. This similarity between liposomes and chylomicrons allows liposomal molecules to exploit the same metabolic pathways that the organism generally enacts for chylomicrons. The ingested iron liposome in the intestinal lumen is absorbed directly by the M cells (and not by the enterocytes), cells that originate from the lymphatic system and are located throughout the small intestine. Subsequently, the liposome is incorporated by endocytosis from the macrophages and through the lymphatic torrent reaches, intact, the hepatocytes. Within the hepatocytes the liposome will be “opened” by the lysosomal enzymes thus making the iron available for the organism. The absorption and bioavailability of the liposomal iron with respect to the other iron salts, commonly used in the formulation of the products present on the market, has been evaluated on an animal model. These studies have shown that thanks to the liposomal technology, the absorption of liposomal pyrophosphate iron is 3.5 times greater than free pyrophosphate iron, 2.7 times higher than iron sulfate and 4.1 times higher than the iron gluconate. In addition, the plasma concentration of liposomal iron was found to be maximal after two hours from intake, which ensures greater bioavailability of the element for all metabolic processes.

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Magnesium against stress


The effects of magnesium

Maintaining the correct magnesium levels helps to prevent and calm stress-related symptoms.

It is widely documented that magnesium deficiency is associated with irritability, nervousness, tension, restlessness, anxiety, apprehension, difficulty in concentration, general apathy, loss of appetite or nervous hunger, mental fatigue, insomnia, premenstrual syndrome, menopausal symptoms, restless legs syndrome, palpitations.

Concretely, the intake of magnesium reduces the excitability of nerves and muscles, reduces the secretion of adrenaline and contributes to the communication processes of nerve cells, helping to regulate the transmission of signals.

In addition, magnesium acts on the nervous system and nocturnal hormones, helping relaxation and a better rest.

Magnesium is an essential mineral for the body: it helps to produce energy, conserve it and use it in the right way and it favors the activity of the nervous system, whose regulation can be altered in some situations like stress, unbalanced feeding and pregnancy.


Magnesium bisglycinate is a form of chelated magnesium in which the element is bound to two glycine molecules.

It is absorbed and poured into the blood more easily through the intestine.

The scientific literature has shown a higher absorption compared to other formulations, as has been shown a poor elimination of the mineral after intake.

The organism therefore succeeds in assimilating it in greater quantity.

Daily magnesium requirement

The daily intake of magnesium through the recommended diet is about 5-6 mg/kg of body weight, which become 10 mg in pregnant women and 15 mg in the child. The magnesium requirement is influenced by the amount of calcium, protein, phosphorus and vitamin D present in the diet and increases in proportion to the levels of cholesterol present in the blood.

The 10 richest magnesium foods:

1. Whole grains
2. Peas and beans
3. Dates
4. Dill (aromatic plant)
5. Bitter cocoa
6. Figs
7. Almonds, hazelnuts and walnuts
8. Soybeans
9. Pumpkin seeds
10. Green leafy vegetables such as spinach and chard


  • The benefits of magnesium in pregnancy

During pregnancy and then during lactation, magnesium requirements increase both for consumption by the fetus and for contingent situations such as nausea and vomiting, which reduce absorption. It is common to hear a pregnant woman complain of continuous muscle cramps, anxiety, insomnia, or even depression, situations in which magnesium supplementation can be self-resolving. But even more important is to know that nowadays numerous scientific studies and clinical practice have demonstrated the magnesium’s ability to reduce the uterine contractile activity. In pregnancy, magnesium is very important: it helps women to relax the uterine area, preventing premature births from occurring.

  • The benefits of magnesium against anxiety

Magnesium helps fight anxiety and is often used in therapies against depression. Its ability to act directly on the nervous system requires additional intake during periods of major stress or if you suffer from panic attacks or other anxious manifestations. It can also be used as a supplement at a difficult time like postpartum depression.

  • The benefits of magnesium as an aid for menstrual pain

Taking magnesium in the period before the cycle can alleviate all the pains and humoral changes related to premenstrual syndrome. It is also very useful during the menopause, because it regulates hot flashes and anxiety and depressive disorders.

  • The benefits of magnesium on the skin

Magnesium helps fight water retention and purify the skin. It is in fact often recommended as an adjuvant for acne treatments. It has a very useful antibacterial function that acts directly on the pimples and on the facial imperfections.

  • The benefits of magnesium against fatigue

Magnesium is the energizing mineral par excellence. It helps not only to relax, but also to recharge, acting directly on the enzymatic processes related to fatigue and which can cause asthenia.

  • The benefits of magnesium on bones

Magnesium helps to fix calcium in the bones, preventing osteoporosis and counteracting the formation of calcareous deposits and arthritis. Its ability to regulate and repair is extremely important for defending and strengthening our bones.

  • The benefits of magnesium against stress

Finally, magnesium acts directly on the nervous system, helping to calm stress and all the problems that derive from it, from headaches to palpitations, from stomach acid to muscle tension. Taking the amount necessary in your diet is essential because a deficit of this mineral could in turn be a cause of the increase in symptoms related to stress.

Rosa Canina source of vitamin C


Rosa Canina is the most widespread rose species in the world belonging to the Rosaceae family. It is a spontaneous plant with a thorny shrub that can reach 3 meters in height. It grows in the hills and in the countryside especially on large and very sunny areas. The plant is named “canine” by Pliny the Elder (1st century AD), who described the healing of a soldier suffering from rabies thanks to a decoction made from these berries.

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